Zverev beat the 19-year-old Australian 6-2 6-4 in the warm-up event for the US Open to claim a third ATP title this year after wins in Munich and Madrid.
After his semifinal win Saturday, the 21-year-old joked that he was the "only one that's allowed to buy a drink in the USA, right?" After a 125 miles per hour ace flew past, de Minaur nodded.
Rublev broke DeMinaur at love to close out the first set and raced ahead 6-2 in the tiebreaker, but De Minaur hit an ace, service victor and forehand victor to pull level, then forced a third set on a Rublev mis-hit and wide backhand.
"I did everything I could to recover", De Minaur said.
Zverev then wrapped up the victory with his fifth match point as he resumed service, winning the second set 6-4.More news: Mauricio Pochettino hails Tottenham Hotspur's Academy after successful USA tour
It's only the second career ATP final for De Minaur, the son of a Spanish mother and Uruguayan father who lost to Russian Daniil Medvedev in January's Sydney final.
Zverev then held to finish the 74-minute match when De Minaur netted a backhand.
The Zverev power off both wings-and the German's backhand is more than a match for his forehand-together with his big serve and real ability at the net courtesy of his doubles play with elder brother Mischa, was making him nearly impenetrable. "He played some great tennis and was too good for me".
When de Minaur was serving, meanwhile, Zverev generated 11 break points, converting three. Rublev beat local product Denis Kudla, a Junior Tennis Champions Center, 6-1, 6-4 before losing in three sets to de Minaur. "I encountered a bigger and better player today".
"This is wonderful for tennis", Zverev said. "He hit me off the court and he was too good". I mean, four next-gen players in the semifinals, that's incredible for tennis I think. "It helped us out a lot to have parents to teach us the technique". His reaction: "My God, that hasn't happened to me before". "I just need to stay humble, serve well, play well from the baseline and be aggressive".More news: James Corden reveals how Kanye West cost 'The Late Late Show' $45,000
The second set was tighter.
In the companion WTA event, two-time Grand Slam champion Svetlana Kuznetsova of Russian Federation advanced by defeating Kazakh eighth seed Yulia Putintseva 6-2, 6-2 in a quarter-final rained out Friday.
The "tactic", if you could call it that, didn't provide any magic cure however, with Tsitsipas - who this year produced his best grand slam result of a fourth round appearance, at Wimbledon - going on to be humbled 6-2 6-4. The three-time major champion, coming back from hip surgery, finished his most recent match at 3 a.m. Friday and made a decision to withdraw rather than play again so soon afterward.
Murray is working his way back into form after having surgery on his right hip and being sidelined for 11 months.More news: Iran sanctions: U.S. can't stop our oil exports, says minister
- Putin recognized that it is forbidden in Ukraine Steven Seagal to promote
- Kourtney Kardashian & Younes Bendjima Split
- Rand Paul says he delivered Trump letter to Putin
- Elliott holds off Truex at Watkins Glen
- Woods trying something new at PGA Championship
- Samsung Starts Mass Producing Cheaper 4TB SSDs
- Ben Stokes trial shown CCTV footage of 'melee outside nightclub'
- Warner Bros. Reportedly Interested In James Gunn After Disney Firing
- Trump going ahead with tariffs on $16B in Chinese imports
- NASA to launch first-ever solar mission to ‘touch the sun’