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Experimental Treatment Puts Breast Cancer Patient In Full Remission

05 June 2018

In addition, a recent study says chemo does not improve survival, that most women can be safely treated with just surgery and hormone blockers.

A new U.S. study, TAILORx, has shown that up to 70% of these women could avoid this painful treatment, which has multiple side effects.

A long-awaited clinic trial is changing the way doctors are treating some patients. These included hormone-driven breast cancer, ovarian cancer and prostate cancer. Generally, after surgery, such patients receive endocrine therapy, such as tamoxifen, which is created to block the cancer-spurring effects of hormones.

The trial results showed that for women in the intermediate recurrence score group, endocrine therapy was no less effective than hormone therapy plus chemotherapy at prolonging disease-free survival.

Sunday's results came from a federally sponsored trial called TailorX, which was created to help doctors more precisely tailor treatments for early-stage breast cancer.

The method, while still in its infancy, also shrank hard-to-treat tumors in six other patients with colon and cervical cancers, said Steven Rosenberg, chief of surgery at the institute where it is being studied.

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Until now, chemotherapy was highly recommended with a result greater than 25, and below 10 it was not.

Those who score 26 or higher on the scale do benefit and now receive chemotherapy.

"Now, the vast majority of patients can potentially receive benefits from immunotherapy instead", he added.

But doctors have been unsure how to treat women with scores in the intermediate range of 11 and 25. Nine-year rates were similar for iDFS (83.3% vs 84.3%), DRFI (94.5% vs 95.0%), RFI (92.2% vs 92.9%), and OS (93.9% vs 93.8%) for the RS 11 to 25 arm. However, most breast cancer occurs in older women.

In the latest study, a team extracted immune cells called lymphocytes from the patient, tweaked them in the lab, then reinjected them. Among younger women with scores 16 to 25, outcomes were slightly better in the chemotherapy group.

A POTENTIAL cure for cancer may have been found in the USA after a woman suffering from an "incurable" breast cancer that had spread to some of her organs was cured of the killer illness.

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"Side effects, such as hair loss, severe pain and infertility, can be utterly devastating and linger long after they walk out the hospital doors". The National Cancer Institute provided $36 million, and $4.5 million of it came from the money collected from the stamp.

"When you get diagnosed with breast cancer, you're like, 'What?' You know, 'I work out".

Laszlo Radvanyi, scientific director of the Ontario Institute for Cancer Research, told TheGuardian it was an "unprecedented" result, and could dawn in a completely new age of cancer treatment. The treatment can cause unpleasant side effects, some of which can put a woman's life at risk.

The Oncotype DX genetic test has been available on the NHS since 2013, but the National Institute for Health and Care Excellence (Nice) is now updating its guidance on whether it should be recommended for use.

"Because this is a huge study". In this case study the researchers observed the tumors disappearing at a remarkable rate.

"This is a hugely exciting first in the treatment of advanced breast cancer". "They are going to change treatment - and remove uncertainty for women making decisions".

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Experimental Treatment Puts Breast Cancer Patient In Full Remission