Chad Kuhl (5-8) allowed five runs - four earned - on four hits over five innings in the loss.
Polanco (hamstring) is not in the lineup for Sunday's game against the Blue Jays. However, Happ worked his way out of trouble allowing one run while leaving runners in scoring position.More news: English-fluent new Foreign Minister Kono makes worldwide debut at ASEAN gathering
Justin Smoak and Darwin Barney added solo homers for the Blue Jays, who have won nine of 13 at home.
Pittsburgh opened the scoring in the top half of the first on an RBI single from David Freese.More news: USA soldiers killed in Iraq, 5 wounded
This marks the second time Martin has hit the DL this year after missing time due to a nerve issue in his left shoulder in May. Measured at 452 feet, it was Donaldson's longest homer of the season. The left-hander tossed six innings of one-run ball while striking out eight and walking three.
Lopez started his first game with the Blue Jays on Wednesday, becoming the sixth catcher to start behind the plate for Toronto this season, a franchise record.More news: Fargo Public Library to host two solar eclipse events
He has the 13th most wins amongst active Major League Baseball managers and will go for win No. 701 on Monday against the Tampa Bay Rays.
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