He almost spun a triple-double in Game 2, reviving talk of "Playoff Rondo" with 11 points, 14 assists, nine rebounds and five steals.
Jae Crowder scored 16 points as five Celtics reached double figures. The Bulls didn't trail in the second half, using a 10-0 scoring run - which included eight points from Wade - to build a 19-point lead in the fourth quarter on the way to the convincing win.
The Bulls and Celtics don't square off again until Friday, but here's three takeaways from Game 2 to tide you over until then.
Thomas nearly lifted the Eastern Conference top seeds to victory with two late baskets in their best-of-seven first-round series opener against the Bulls, but the visitors survived to draw first blood, 106-102.
Thomas did not speak to the media afterward and will now head to Tacoma, Washington to be with his family to finalize funeral arrangements for his sister, Chyna Thomas.More news: 10 things to know about Westbrook's triple-double record
There may not be another line of work that couldn't wait at least a day or two for Thomas to overcome the grief of losing his kid sister in a auto crash the day before the playoffs began.
Celtics: Finished with 16 turnovers, leading to 23 Chicago points.Thomas shot 7 of 13 from the free throw line.
After Jimmy Butler hit a jumper in the lane over Marcus Smart in the second quarter one Celtics fan in the crowd, who identified himself as Mike S. from Everett, turned to his friend and said, "Why didn't we trade for Jimmy?" Butler also posted eight rebounds and eight assists. He scored 20 points but was just 6 of 15 from the floor, including 1 of 5 from 3-point range.
"We don't have home-court advantage, so we had to get one here if we want to win this series", Wade said.
His coach Brad Stevens gave Thomas the option of playing or missing the first game or two of the playoffs to be with his family.More news: Korea leader oversees special forces op as tensions soar
What is happening?!? The Bulls offense, a not-great unit, put up 111 points on the Celtics in (what you'd think) was a must-win game for them.
Boston's defense really had no answer for Bobby Portis and Jimmy Butler in Game 1.
"That hate is that respect", Wade said. Khris Middleton added 20 points for Milwaukee, who will seek to regain the series edge when they host game three on Thursday.
Having edged out the opening game of the series, Chicago proved that was no fluke in Game 2 as Fred Hoiberg's squad again played physical, old-school basketball to beat down the Celtics.More news: Aaron Hernandez's brain will be examined for CTE
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